Detalhe da pesquisa
1.
CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression.
Cell
; 168(5): 801-816.e13, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28215704
2.
The origin and evolution of mutations in acute myeloid leukemia.
Cell
; 150(2): 264-78, 2012 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22817890
3.
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.
Nature
; 518(7540): 552-555, 2015 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25487151
4.
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing.
Nature
; 481(7382): 506-10, 2012 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22237025
5.
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.
N Engl J Med
; 368(22): 2059-74, 2013 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23634996
6.
Genomic impact of transient low-dose decitabine treatment on primary AML cells.
Blood
; 121(9): 1633-43, 2013 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23297133
7.
Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia.
JAMA
; 314(8): 811-22, 2015 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26305651
8.
Biome representational in silico karyotyping.
Genome Res
; 21(4): 626-33, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21324882
9.
DNMT3A mutations in acute myeloid leukemia.
N Engl J Med
; 363(25): 2424-33, 2010 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21067377
10.
Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators.
Blood Cancer Discov
; 2(6): 586-599, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34778799
11.
Clonal dynamics of donor-derived myelodysplastic syndrome after unrelated hematopoietic cell transplantation for high-risk pediatric B-lymphoblastic leukemia.
Cold Spring Harb Mol Case Stud
; 4(5)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29891567
12.
Germline SAMD9 and SAMD9L mutations are associated with extensive genetic evolution and diverse hematologic outcomes.
JCI Insight
; 3(14)2018 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30046003
13.
The genomic landscape of pediatric myelodysplastic syndromes.
Nat Commun
; 8(1): 1557, 2017 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29146900
14.
PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia.
J Clin Invest
; 126(1): 85-98, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26595813
15.
Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B-lymphoblastic leukemia.
Exp Hematol
; 44(7): 603-13, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27181063
16.
The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers.
Cancer Cell
; 25(4): 442-54, 2014 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24656771
17.
Functional heterogeneity of genetically defined subclones in acute myeloid leukemia.
Cancer Cell
; 25(3): 379-92, 2014 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24613412
18.
Notch signaling in acute promyelocytic leukemia.
Leukemia
; 27(7): 1548-1557, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23455394
19.
Effect of circadian clock gene mutations on nonvisual photoreception in the mouse.
Invest Ophthalmol Vis Sci
; 53(1): 454-60, 2012 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22159024
20.
Expression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA mice.
PLoS One
; 7(10): e46529, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23056333